H7N9 influenza split vaccine with SWE oil-in-water adjuvant greatly enhances cross-reactive humoral immunity and protection against severe pneumonia in ferrets

Until universal influenza vaccines become available, pandemic preparedness should include developing classical vaccines against potential pandemic influenza subtypes. We here show that addition of SWE adjuvant, a squalene-in-water emulsion, to H7N9 split influenza vaccine clearly enhanced functional...

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Bibliografiske detaljer
Udgivet i:NPJ Vaccines
Main Authors: de Jonge, Jørgen, van Dijken, Harry, de Heij, Femke, Spijkers, Sanne, Mouthaan, Justin, de Jong, Rineke, Roholl, Paul, Adami, Eduardo Alfredo, Akamatsu, Milena Apetito, Ho, Paulo Lee, Brunner, Livia, Collin, Nicolas, Friede, Martin, Ferreira, José A., Luytjes, Willem
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214439/
https://ncbi.nlm.nih.gov/pubmed/32411401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0187-4
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