H7N9 influenza split vaccine with SWE oil-in-water adjuvant greatly enhances cross-reactive humoral immunity and protection against severe pneumonia in ferrets

Until universal influenza vaccines become available, pandemic preparedness should include developing classical vaccines against potential pandemic influenza subtypes. We here show that addition of SWE adjuvant, a squalene-in-water emulsion, to H7N9 split influenza vaccine clearly enhanced functional...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: de Jonge, Jørgen, van Dijken, Harry, de Heij, Femke, Spijkers, Sanne, Mouthaan, Justin, de Jong, Rineke, Roholl, Paul, Adami, Eduardo Alfredo, Akamatsu, Milena Apetito, Ho, Paulo Lee, Brunner, Livia, Collin, Nicolas, Friede, Martin, Ferreira, José A., Luytjes, Willem
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214439/
https://ncbi.nlm.nih.gov/pubmed/32411401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0187-4
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