Immunogenicity and Cross Protection in Mice Afforded by Pandemic H1N1 Live Attenuated Influenza Vaccine Containing Wild-Type Nucleoprotein

Since conserved viral proteins of influenza virus, such as nucleoprotein (NP) and matrix 1 protein, are the main targets for virus-specific CD8+ cytotoxic T-lymphocytes (CTLs), we hypothesized that introduction of the NP gene of wild-type virus into the genome of vaccine reassortants could lead to b...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Rekstin, Andrey, Isakova-Sivak, Irina, Petukhova, Galina, Korenkov, Daniil, Losev, Igor, Smolonogina, Tatiana, Tretiak, Tatiana, Donina, Svetlana, Shcherbik, Svetlana, Bousse, Tatiana, Rudenko, Larisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292185/
https://ncbi.nlm.nih.gov/pubmed/28210631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9359276
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