GTS-21 attenuates loss of body mass, muscle mass and function in rats having systemic inflammation with and without disuse atrophy

Muscle changes of critical illness are attributed to systemic inflammatory responses and disuse atrophy. GTS-21 (3-(2,4-dimethoxy-benzylidene)anabaseine), also known as DMBX-A) is a synthetic derivative of the natural product anabaseine that acts as an agonist at α7-acetylcholine receptors (α7nAChRs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pflugers Arch
Egile Nagusiak: Schaller, Stefan J., Nagashima, Michio, Schönfelder, Martin, Sasakawa, Tomoki, Schulz, Fabian, Khan, Mohammed A. S., Kem, William R., Schneider, Gerhard, Schlegel, Jürgen, Lewald, Heidrun, Blobner, Manfred, Jeevendra Martyn, J. A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330254/
https://ncbi.nlm.nih.gov/pubmed/30006848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-018-2180-6
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