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GTS-21 attenuates loss of body mass, muscle mass and function in rats having systemic inflammation with and without disuse atrophy
Muscle changes of critical illness are attributed to systemic inflammatory responses and disuse atrophy. GTS-21 (3-(2,4-dimethoxy-benzylidene)anabaseine), also known as DMBX-A) is a synthetic derivative of the natural product anabaseine that acts as an agonist at α7-acetylcholine receptors (α7nAChRs...
Tallennettuna:
| Julkaisussa: | Pflugers Arch |
|---|---|
| Päätekijät: | , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6330254/ https://ncbi.nlm.nih.gov/pubmed/30006848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-018-2180-6 |
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