Lack of caspase-3 attenuates immobilization-induced muscle atrophy and loss of tension generation along with mitigation of apoptosis and inflammation

INTRODUCTION: Immobilization by casting induces disuse muscle atrophy (DMA). METHODS: Using wild type (WT) and caspase-3 knockout (KO) mice, we evaluated the effect of caspase-3 on muscle mass, apoptosis and inflammation during DMA. RESULTS: Caspase-3 deficiency significantly attenuated muscle mass...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhu, Shimei, Nagashima, Michio, Khan, Mahammad A.S, Yasuhara, Shingo, Kaneki, Masao, Jeevendra Martyn, J. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634903/
https://ncbi.nlm.nih.gov/pubmed/23401051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.23642
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge