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Lack of caspase-3 attenuates immobilization-induced muscle atrophy and loss of tension generation along with mitigation of apoptosis and inflammation
INTRODUCTION: Immobilization by casting induces disuse muscle atrophy (DMA). METHODS: Using wild type (WT) and caspase-3 knockout (KO) mice, we evaluated the effect of caspase-3 on muscle mass, apoptosis and inflammation during DMA. RESULTS: Caspase-3 deficiency significantly attenuated muscle mass...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3634903/ https://ncbi.nlm.nih.gov/pubmed/23401051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.23642 |
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