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Obesity-Induced Insulin Resistance and Hyperglycemia: Etiological Factors and Molecular Mechanisms
Obesity is a major cause of type 2 diabetes, clinically evidenced as hyperglycemia. The altered glucose homeostasis is caused by faulty signal transduction via the insulin signaling proteins, which results in decreased glucose uptake by the muscle, altered lipogenesis, and increased glucose output b...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896971/ https://ncbi.nlm.nih.gov/pubmed/18580184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181799d45 |
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