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Obesity-Induced Insulin Resistance and Hyperglycemia: Etiological Factors and Molecular Mechanisms

Obesity is a major cause of type 2 diabetes, clinically evidenced as hyperglycemia. The altered glucose homeostasis is caused by faulty signal transduction via the insulin signaling proteins, which results in decreased glucose uptake by the muscle, altered lipogenesis, and increased glucose output b...

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Detalhes bibliográficos
Main Authors: Jeevendra Martyn, J.A., Kaneki, Masao, Yasuhara, Shingo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896971/
https://ncbi.nlm.nih.gov/pubmed/18580184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181799d45
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