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Anesthesia with Disuse Leads to Autophagy Upregulation in the Skeletal Muscle

BACKGROUND: It has been known that skeletal muscles show atrophic changes after prolonged sedation or general anesthesia. Whether these effects are due to anesthesia itself or to disuse during anesthesia has not been fully clarified. Autophagy dysregulation has been implicated in muscle wasting cond...

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Detalles Bibliográficos
Publicado en:Anesthesiology
Main Authors: Kashiwagi, Aki, Hosokawa, Sachiko, Maeyama, Yoshihiro, Ueki, Ryusuke, Kaneki, Masao, Martyn, J.A. Jeevendra, Yasuhara, Shingo
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439320/
https://ncbi.nlm.nih.gov/pubmed/25501690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000561
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