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A Single Injection of Botulinum Toxin Decreases the Margin of Safety of Neurotransmission at Local and Distant Sites

BACKGROUND: We tested the hypothesis that a single injection of botulinum toxin not only has local, but also distant effects on muscle function, biochemistry, and pharmacodynamics of atracurium. METHODS: Botulinum toxin (2.5U) was injected into the tibialis muscle of anesthetized rats (n=26). The co...

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Autors principals: Frick, Christiane G, Fink, Heidrun, Blobner, Manfred, Martyn, Jeevendra
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243776/
https://ncbi.nlm.nih.gov/pubmed/22003222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31823526bf
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