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Multi-SKAT: General framework to test for rare variant association with multiple phenotypes

In genetic association analysis, a joint test of multiple distinct phenotypes can increase power to identify sets of trait-associated variants within genes or regions of interest. Existing multi-phenotype tests for rare variants make specific assumptions about the patterns of association with underl...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Dutta, Diptavo, Scott, Laura, Boehnke, Michael, Lee, Seunggeun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330125/
https://ncbi.nlm.nih.gov/pubmed/30298564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22156
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