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N-degron and C-degron pathways of protein degradation

This perspective is partly review and partly proposal. N-degrons and C-degrons are degradation signals whose main determinants are, respectively, the N-terminal and C-terminal residues of cellular proteins. N-degrons and C-degrons include, to varying extents, adjoining sequence motifs, and also inte...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autor: Varshavsky, Alexander
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329975/
https://ncbi.nlm.nih.gov/pubmed/30622213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816596116
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