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Recognition of nonproline N-terminal residues by the Pro/N-degron pathway

Eukaryotic N-degron pathways are proteolytic systems whose unifying feature is their ability to recognize proteins containing N-terminal (Nt) degradation signals called N-degrons, and to target these proteins for degradation by the 26S proteasome or autophagy. GID4, a subunit of the GID ubiquitin li...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Dong, Cheng, Chen, Shun-Jia, Melnykov, Artem, Weirich, Sara, Sun, Kelly, Jeltsch, Albert, Varshavsky, Alexander, Min, Jinrong
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322002/
https://ncbi.nlm.nih.gov/pubmed/32513738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007085117
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