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Tying up loose ends: the N-degron and C-degron pathways of protein degradation

Selective protein degradation by the ubiquitin-proteasome system (UPS) is thought to be governed primarily by the recognition of specific motifs — degrons — present in substrate proteins. The ends of proteins — the N- and C-termini – have unique properties, and an important subset of protein–protein...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Timms, Richard T., Koren, Itay
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458402/
https://ncbi.nlm.nih.gov/pubmed/32627813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20191094
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