Microbubble-mediated delivery of human adenoviruses does not elicit innate and adaptive immunity response in an immunocompetent mouse model of prostate cancer

BACKGROUND: Gene transfer to malignant sites using human adenoviruses (hAds) has been limited because of their immunogenic nature and host specificity. Murine cells often lack some of the receptors needed for hAds attachment, thus murine cells are generally non-permissive for human adenoviral infect...

詳細記述

保存先:
書誌詳細
出版年:J Transl Med
主要な著者: De Carlo, Flavia, Thomas, Litty, Brooke, Bell, Varney, Elliot T., Nande, Rounak, Boskovic, Olivia, Marshall, Gailen D., Claudio, Pier Paolo, Howard, Candace M.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329087/
https://ncbi.nlm.nih.gov/pubmed/30635014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1771-0
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