Loss of the mitochondrial i‐AAA protease YME1L leads to ocular dysfunction and spinal axonopathy

Disturbances in the morphology and function of mitochondria cause neurological diseases, which can affect the central and peripheral nervous system. The i‐AAA protease YME1L ensures mitochondrial proteostasis and regulates mitochondrial dynamics by processing of the dynamin‐like GTPase OPA1. Mutatio...

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Detalles Bibliográficos
Publicado en:EMBO Mol Med
Main Authors: Sprenger, Hans‐Georg, Wani, Gulzar, Hesseling, Annika, König, Tim, Patron, Maria, MacVicar, Thomas, Ahola, Sofia, Wai, Timothy, Barth, Esther, Rugarli, Elena I, Bergami, Matteo, Langer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328943/
https://ncbi.nlm.nih.gov/pubmed/30389680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809288
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