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m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration
The function of mitochondria depends on ubiquitously expressed and evolutionary conserved m-AAA proteases in the inner membrane. These ATP-dependent peptidases form hexameric complexes built up of homologous subunits. AFG3L2 subunits assemble either into homo-oligomeric isoenzymes or with SPG7 (para...
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| Publicado no: | Cell Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835776/ https://ncbi.nlm.nih.gov/pubmed/29451229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2018.17 |
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