Astrocyte‐specific deletion of the mitochondrial m‐AAA protease reveals glial contribution to neurodegeneration

Mitochondrial dysfunction causes neurodegeneration but whether impairment of mitochondrial homeostasis in astrocytes contributes to this pathological process remains largely unknown. The m‐AAA protease exerts quality control and regulatory functions crucial for mitochondrial homeostasis. AFG3L2, whi...

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Bibliografske podrobnosti
izdano v:Glia
Main Authors: Murru, Sara, Hess, Simon, Barth, Esther, Almajan, Eva R., Schatton, Désirée, Hermans, Steffen, Brodesser, Susanne, Langer, Thomas, Kloppenburg, Peter, Rugarli, Elena I.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618114/
https://ncbi.nlm.nih.gov/pubmed/30989755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23626
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