RGS9‐2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models

Dopamine D2 receptor signaling is central for striatal function and movement, while abnormal activity is associated with neurological disorders including the severe early‐onset DYT1 dystonia. Nevertheless, the mechanisms that regulate D2 receptor signaling in health and disease remain poorly underst...

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Detalles Bibliográficos
Publicado en:EMBO Mol Med
Main Authors: Bonsi, Paola, Ponterio, Giulia, Vanni, Valentina, Tassone, Annalisa, Sciamanna, Giuseppe, Migliarini, Sara, Martella, Giuseppina, Meringolo, Maria, Dehay, Benjamin, Doudnikoff, Evelyne, Zachariou, Venetia, Goodchild, Rose E, Mercuri, Nicola B, D'Amelio, Marcello, Pasqualetti, Massimo, Bezard, Erwan, Pisani, Antonio
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328939/
https://ncbi.nlm.nih.gov/pubmed/30552094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809283
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