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Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice
Background: Microglia activation contributes to chronic pain and to the adverse effects of opiate use such as analgesic tolerance and opioid-induced hyperalgesia. Both mu opioid receptor (MOR) encoded by Oprm1/OPRM1 gene and toll like receptor 4 (TLR4) have been reported to mediate these morphine ef...
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| Publicado no: | Front Psychiatry |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328486/ https://ncbi.nlm.nih.gov/pubmed/30662412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2018.00726 |
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