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Mu-opioid receptors are not necessary for nortriptyline treatment of neuropathic allodynia

Tricyclic antidepressants (TCAs) are among the first line treatments clinically recommended against neuropathic pain. However, the mechanism by which they alleviate pain is still unclear. Pharmacological and genetic approaches evidenced a critical role of delta-opioid receptors (DORs) in the therape...

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Detalhes bibliográficos
Publicado no:Eur J Pain
Main Authors: Bohren, Yohann, Karavelic, Dzenan, Tessier, Luc-Henri, Yalcin, Ipek, Gavériaux-Ruff, Claire, Kieffer, Brigitte L., Freund-Mercier, Marie-José, Barrot, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469366/
https://ncbi.nlm.nih.gov/pubmed/20056557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpain.2009.11.014
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