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Exposure of Barrett’s and esophageal adenocarcinoma cells to Bile acids activates EGFR-STAT3 signaling axis via induction of APE1

The development of Barret’s esophagus (BE) and its progression to esophageal adenocarcinoma (EAC) is highly linked to exposure to acidic bile salts due to chronic gastroesophageal reflux disease (GERD). In this study, we investigated the role of Apurinic/apyrimidinic endonuclease 1 /redox effector f...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Bhat, Ajaz A., Lu, Heng, Soutto, Mohammed, Capobianco, Anthony, Rai, Priyamvada, Zaika, Alexander, El-Rifai, Wael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328352/
https://ncbi.nlm.nih.gov/pubmed/29991802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0388-8
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