Crystal structures of VIM‐1 complexes explain active site heterogeneity in VIM‐class metallo‐β‐lactamases

Metallo‐β‐Lactamases (MBLs) protect bacteria from almost all β‐lactam antibiotics. Verona integron‐encoded MBL (VIM) enzymes are among the most clinically important MBLs, with VIM‐1 increasing in carbapenem‐resistant Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae) that are among the har...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS J
Egile Nagusiak: Salimraj, Ramya, Hinchliffe, Philip, Kosmopoulou, Magda, Tyrrell, Jonathan M., Brem, Jürgen, van Berkel, Sander S., Verma, Anil, Owens, Raymond J., McDonough, Michael A., Walsh, Timothy R., Schofield, Christopher J., Spencer, James
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326847/
https://ncbi.nlm.nih.gov/pubmed/30430727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14695
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