Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development

Animal cloning can be achieved through somatic cell nuclear transfer (SCNT), although the live birth rate is relatively low. Recent studies have identified H3K9me3 in donor cells and abnormal Xist activation as epigenetic barriers that impede SCNT. Here we overcome these barriers using a combination...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Matoba, Shogo, Wang, Huihan, Jiang, Lan, Lu, Falong, Iwabuchi, Kumiko A., Wu, Xiaoji, Inoue, Kimiko, Yang, Lin, Press, William, Lee, Jeannie T., Ogura, Atsuo, Shen, Li, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326833/
https://ncbi.nlm.nih.gov/pubmed/30033120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.06.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados