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Privileged Communication Embryonic Development Following Somatic Cell Nuclear Transfer Impeded by Persisting Histone Methylation

Mammalian oocytes can reprogram somatic cells into a totipotent state enabling animal cloning through somatic cell nuclear transfer (SCNT). However, the majority of SCNT embryos fail to develop to term due to undefined reprogramming defects. Here we identify histone H3 lysine 9 trimethylation (H3K9m...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Matoba, Shogo, Liu, Yuting, Lu, Falong, Iwabuchi, Kumiko A., Shen, Li, Inoue, Azusa, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243038/
https://ncbi.nlm.nih.gov/pubmed/25417163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.055
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