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Genomic imprinting of Xist by maternal H3K27me3

Maternal imprinting at the Xist gene is essential to achieve paternal allele-specific imprinted X-chromosome inactivation (XCI) in female mammals. However, the mechanism underlying Xist imprinting is unclear. Here we show that the Xist locus is coated with a broad H3K27me3 domain that is established...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Inoue, Azusa, Jiang, Lan, Lu, Falong, Zhang, Yi
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710138/
https://ncbi.nlm.nih.gov/pubmed/29089420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.304113.117
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