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Maternal Eed knockout causes loss of H3K27me3 imprinting and random X inactivation in the extraembryonic cells
Genomic imprinting is essential for mammalian development. Recent studies have revealed that maternal histone H3 Lys27 trimethylation (H3K27me3) can mediate DNA methylation-independent genomic imprinting. However, the regulatory mechanisms and functions of this new imprinting mechanism are largely u...
में बचाया:
| में प्रकाशित: | Genes Dev |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Cold Spring Harbor Laboratory Press
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295166/ https://ncbi.nlm.nih.gov/pubmed/30463900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.318675.118 |
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