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Maternal Eed knockout causes loss of H3K27me3 imprinting and random X inactivation in the extraembryonic cells

Genomic imprinting is essential for mammalian development. Recent studies have revealed that maternal histone H3 Lys27 trimethylation (H3K27me3) can mediate DNA methylation-independent genomic imprinting. However, the regulatory mechanisms and functions of this new imprinting mechanism are largely u...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Inoue, Azusa, Chen, Zhiyuan, Yin, Qiangzong, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295166/
https://ncbi.nlm.nih.gov/pubmed/30463900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.318675.118
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