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A tightly regulated and adjustable CRISPR-dCas9 based AND gate in yeast

The robust and precise on and off switching of one or more genes of interest, followed by expression or repression is essential for many biological circuits as well as for industrial applications. However, many regulated systems published to date influence the viability of the host cell, show high b...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Hofmann, Anja, Falk, Johannes, Prangemeier, Tim, Happel, Dominic, Köber, Adrian, Christmann, Andreas, Koeppl, Heinz, Kolmar, Harald
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326796/
https://ncbi.nlm.nih.gov/pubmed/30476163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1191
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