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A tightly regulated and adjustable CRISPR-dCas9 based AND gate in yeast

The robust and precise on and off switching of one or more genes of interest, followed by expression or repression is essential for many biological circuits as well as for industrial applications. However, many regulated systems published to date influence the viability of the host cell, show high b...

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Pubblicato in:Nucleic Acids Res
Autori principali: Hofmann, Anja, Falk, Johannes, Prangemeier, Tim, Happel, Dominic, Köber, Adrian, Christmann, Andreas, Koeppl, Heinz, Kolmar, Harald
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326796/
https://ncbi.nlm.nih.gov/pubmed/30476163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1191
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