Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

Hippo signaling has been recognized as a key tumor suppressor pathway. Here, we perform a comprehensive molecular characterization of 19 Hippo core genes in 9,125 tumor samples across 33 cancer types using multidimensional “omic” data from The Cancer Genome Atlas. We identify somatic drivers among H...

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Udgivet i:Cell Rep
Main Authors: Wang, Yumeng, Xu, Xiaoyan, Maglic, Dejan, Dill, Michael T., Mojumdar, Kamalika, Ng, Patrick Kwok-Shing, Jeong, Kang Jin, Tsang, Yiu Huen, Moreno, Daniela, Bhavana, Venkata Hemanjani, Peng, Xinxin, Ge, Zhongqi, Chen, Hu, Li, Jun, Chen, Zhongyuan, Zhang, Huiwen, Han, Leng, Du, Di, Creighton, Chad J., Mills, Gordon B., Camargo, Fernando, Liang, Han
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326181/
https://ncbi.nlm.nih.gov/pubmed/30380420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.001
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