A-to-I–edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis

Both miRNAs and A-to-I RNA editing, a widespread nucleotide modification mechanism, have recently emerged as key players in cancer pathophysiology. However, the functional impact of RNA editing of miRNAs in cancer remains largely unexplored. Here, we focused on an ADAR2-catalyzed RNA editing site wi...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Xu, Xiaoyan, Wang, Yumeng, Mojumdar, Kamalika, Zhou, Zhicheng, Jeong, Kang Jin, Mangala, Lingegowda S., Yu, Shuangxing, Tsang, Yiu Huen, Rodriguez-Aguayo, Cristian, Lu, Yiling, Lopez-Berestein, Gabriel, Sood, Anil K., Mills, Gordon B., Liang, Han
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877318/
https://ncbi.nlm.nih.gov/pubmed/31682236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123396
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