A-to-I–edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis

Both miRNAs and A-to-I RNA editing, a widespread nucleotide modification mechanism, have recently emerged as key players in cancer pathophysiology. However, the functional impact of RNA editing of miRNAs in cancer remains largely unexplored. Here, we focused on an ADAR2-catalyzed RNA editing site wi...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Xu, Xiaoyan, Wang, Yumeng, Mojumdar, Kamalika, Zhou, Zhicheng, Jeong, Kang Jin, Mangala, Lingegowda S., Yu, Shuangxing, Tsang, Yiu Huen, Rodriguez-Aguayo, Cristian, Lu, Yiling, Lopez-Berestein, Gabriel, Sood, Anil K., Mills, Gordon B., Liang, Han
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877318/
https://ncbi.nlm.nih.gov/pubmed/31682236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123396
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