Comprehensive assessment of computational algorithms in predicting cancer driver mutations

BACKGROUND: The initiation and subsequent evolution of cancer are largely driven by a relatively small number of somatic mutations with critical functional impacts, so-called driver mutations. Identifying driver mutations in a patient’s tumor cells is a central task in the era of precision cancer me...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Chen, Hu, Li, Jun, Wang, Yumeng, Ng, Patrick Kwok-Shing, Tsang, Yiu Huen, Shaw, Kenna R., Mills, Gordon B., Liang, Han
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033911/
https://ncbi.nlm.nih.gov/pubmed/32079540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01954-z
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