PARP inhibitors affect growth, survival and radiation susceptibility of human alveolar and embryonal rhabdomyosarcoma cell lines

PURPOSE: PARP inhibitors (PARPi) are used in a wide range of human solid tumours but a limited evidence is reported in rhabdomyosarcoma (RMS), the most frequent childhood soft-tissue sarcoma. The cellular and molecular effects of Olaparib, a specific PARP1/2 inhibitor, and AZD2461, a newly synthesiz...

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Detaylı Bibliyografya
Yayımlandı:J Cancer Res Clin Oncol
Asıl Yazarlar: Camero, Simona, Ceccarelli, Simona, De Felice, Francesca, Marampon, Francesco, Mannarino, Olga, Camicia, Lucrezia, Vescarelli, Enrica, Pontecorvi, Paola, Pizer, Barry, Shukla, Rajeev, Schiavetti, Amalia, Mollace, Maria Giovanna, Pizzuti, Antonio, Tombolini, Vincenzo, Marchese, Cinzia, Megiorni, Francesca, Dominici, Carlo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2018
Konular:
Original Article – Cancer Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326011/
https://ncbi.nlm.nih.gov/pubmed/30357520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-018-2774-6
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