OTX015 Epi-Drug Exerts Antitumor Effects in Ovarian Cancer Cells by Blocking GNL3-Mediated Radioresistance Mechanisms: Cellular, Molecular and Computational Evidence

SIMPLE SUMMARY: The outcome for women diagnosed with ovarian cancer (OC), the most aggressive gynecological tumor worldwide, remains very poor. Encouraging therapeutic impact of epigenetic drugs has been suggested in a wide range of human solid tumors, including OC. The present study assessed the in...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Megiorni, Francesca, Camero, Simona, Pontecorvi, Paola, Camicia, Lucrezia, Marampon, Francesco, Ceccarelli, Simona, Anastasiadou, Eleni, Bernabò, Nicola, Perniola, Giorgia, Pizzuti, Antonio, Benedetti Panici, Pierluigi, Tombolini, Vincenzo, Marchese, Cinzia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059141/
https://ncbi.nlm.nih.gov/pubmed/33806232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13071519
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