Crizotinib-induced antitumour activity in human alveolar rhabdomyosarcoma cells is not solely dependent on ALK and MET inhibition

BACKGROUND: Rhabdomyosarcoma (RMS) is the most commonly diagnosed malignant soft tissue tumour in children and adolescents. Aberrant expression of Anaplastic Lymphoma Kinase (ALK) and MET gene has been implicated in the malignant progression of RMS, especially in the alveolar subtype. This observati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Clin Cancer Res
Prif Awduron: Megiorni, Francesca, McDowell, Heather P., Camero, Simona, Mannarino, Olga, Ceccarelli, Simona, Paiano, Milena, Losty, Paul D., Pizer, Barry, Shukla, Rajeev, Pizzuti, Antonio, Clerico, Anna, Dominici, Carlo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596370/
https://ncbi.nlm.nih.gov/pubmed/26445453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0228-4
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