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The Influence of Normalization Weight in Population Pharmacokinetic Covariate Models
In covariate (sub)models of population pharmacokinetic models, most covariates are normalized to the median value; however, for body weight, normalization to 70 kg or 1 kg is often applied. In this article, we illustrate the impact of normalization weight on the precision of population clearance (CL...
שמור ב:
| הוצא לאור ב: | Clin Pharmacokinet |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Springer International Publishing
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325985/ https://ncbi.nlm.nih.gov/pubmed/29572663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0652-7 |
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