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Cyclin-dependent kinase 4 (CDK4) and CDK6 together with D-type cyclins (D1, D2 and D3) to promote cell cycle entry and progression through G1 by inactivating retinoblastoma protein (RB) by inhibiting an INK4 family of CDK inhibitors (CDKN2A/B). Selective cyclin-dependent kinase inhibitors are game c...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Gul, Anita, Leyland-Jones, Brain, Dey, Nandini, De, Pradip
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325472/
https://ncbi.nlm.nih.gov/pubmed/30662797
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