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A combination of the PI3K pathway inhibitor plus cell cycle pathway inhibitor to combat endocrine resistance in hormone receptor-positive breast cancer: a genomic algorithm-based treatment approach

Cyclin-dependent kinase 4 (CDK4) and CDK6 together with D-type cyclins (D1, D2 and D3) to promote cell cycle entry and progression through G1 by inactivating retinoblastoma protein (RB) by inhibiting an INK4 family of CDK inhibitors (CDKN2A/B). Selective cyclin-dependent kinase inhibitors are game c...

詳細記述

保存先:
書誌詳細
出版年:Am J Cancer Res
主要な著者: Gul, Anita, Leyland-Jones, Brain, Dey, Nandini, De, Pradip
フォーマット: Artigo
言語:Inglês
出版事項: e-Century Publishing Corporation 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325472/
https://ncbi.nlm.nih.gov/pubmed/30662797
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