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Targeting ubiquitin-activating enzyme induces ER stress–mediated apoptosis in B-cell lymphoma cells
Alterations in the ubiquitin proteasome system (UPS) leave malignant cells in heightened cellular stress, making them susceptible to proteasome inhibition. However, given the limited efficacy of proteasome inhibitors in non-Hodgkin lymphoma (NHL), novel approaches to target the UPS are needed. Here,...
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| 發表在: | Blood Adv |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325297/ https://ncbi.nlm.nih.gov/pubmed/30617217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018026880 |
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