Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma

The antiapoptotic Bcl-2 family member Bfl-1 is up-regulated in many human tumors in which nuclear factor-κB (NF-κB) is implicated and contributes significantly to tumor cell survival and chemoresistance. We previously found that NF-κB induces transcription of bfl-1 and that the Bfl-1 protein is also...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fan, Gaofeng, Simmons, Matthew J., Ge, Sheng, Dutta-Simmons, Jui, Kucharczak, Jérôme, Ron, Yacov, Weissmann, David, Chen, Chiann-Chyi, Mukherjee, Chandreyee, White, Eileen, Gélinas, Céline
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867266/
https://ncbi.nlm.nih.gov/pubmed/20185581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236760
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados