Targeting ubiquitin-activating enzyme induces ER stress–mediated apoptosis in B-cell lymphoma cells

Alterations in the ubiquitin proteasome system (UPS) leave malignant cells in heightened cellular stress, making them susceptible to proteasome inhibition. However, given the limited efficacy of proteasome inhibitors in non-Hodgkin lymphoma (NHL), novel approaches to target the UPS are needed. Here,...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Best, Scott, Hashiguchi, Taylor, Kittai, Adam, Bruss, Nur, Paiva, Cody, Okada, Craig, Liu, Tingting, Berger, Allison, Danilov, Alexey V.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325297/
https://ncbi.nlm.nih.gov/pubmed/30617217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018026880
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars