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Targeting ubiquitin-activating enzyme induces ER stress–mediated apoptosis in B-cell lymphoma cells
Alterations in the ubiquitin proteasome system (UPS) leave malignant cells in heightened cellular stress, making them susceptible to proteasome inhibition. However, given the limited efficacy of proteasome inhibitors in non-Hodgkin lymphoma (NHL), novel approaches to target the UPS are needed. Here,...
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| Publicado no: | Blood Adv |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325297/ https://ncbi.nlm.nih.gov/pubmed/30617217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018026880 |
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