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Central dogma rates and the trade-off between precision and economy in gene expression
Steady-state protein abundance is set by four rates: transcription, translation, mRNA decay and protein decay. A given protein abundance can be obtained from infinitely many combinations of these rates. This raises the question of whether the natural rates for each gene result from historical accide...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325141/ https://ncbi.nlm.nih.gov/pubmed/30622246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07391-8 |
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