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Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells
To perform their regulatory functions, microRNAs (miRNAs) must assemble with any of the four mammalian Argonaute (Ago) family of proteins, Ago1–4, into an effector complex known as the RNA-induced silencing complex (RISC). While the mature miRNA guides the RISC complex to its target mRNA, the Ago pr...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325137/ https://ncbi.nlm.nih.gov/pubmed/30622242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1267-5 |
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