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Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells
To perform their regulatory functions, microRNAs (miRNAs) must assemble with any of the four mammalian Argonaute (Ago) family of proteins, Ago1–4, into an effector complex known as the RNA-induced silencing complex (RISC). While the mature miRNA guides the RISC complex to its target mRNA, the Ago pr...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325137/ https://ncbi.nlm.nih.gov/pubmed/30622242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1267-5 |
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