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The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes
During an adaptive immune response, activated mature B cells give rise to antibody secreting plasma cells to fight infection. B cells undergo antibody class switching to produce different classes of antibodies with varying effector functions. The mammalian/mechanistic target of rapamycin (mTOR) sign...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6324996/ https://ncbi.nlm.nih.gov/pubmed/30530594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800602 |
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