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Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling
Chromosome organization is crucial for genome function. Here, we present a method for visualizing chromosomal DNA at super-resolution and then integrating Hi-C data to produce three-dimensional models of chromosome organization. Using the super-resolution microscopy methods of OligoSTORM and OligoDN...
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| Veröffentlicht in: | PLoS Genet |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6324821/ https://ncbi.nlm.nih.gov/pubmed/30586358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007872 |
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