Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling

Chromosome organization is crucial for genome function. Here, we present a method for visualizing chromosomal DNA at super-resolution and then integrating Hi-C data to produce three-dimensional models of chromosome organization. Using the super-resolution microscopy methods of OligoSTORM and OligoDN...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Nir, Guy, Farabella, Irene, Pérez Estrada, Cynthia, Ebeling, Carl G., Beliveau, Brian J., Sasaki, Hiroshi M., Lee, S. Dean, Nguyen, Son C., McCole, Ruth B., Chattoraj, Shyamtanu, Erceg, Jelena, AlHaj Abed, Jumana, Martins, Nuno M. C., Nguyen, Huy Q., Hannan, Mohammed A., Russell, Sheikh, Durand, Neva C., Rao, Suhas S. P., Kishi, Jocelyn Y., Soler-Vila, Paula, Di Pierro, Michele, Onuchic, José N., Callahan, Steven P., Schreiner, John M., Stuckey, Jeff A., Yin, Peng, Aiden, Erez Lieberman, Marti-Renom, Marc A., Wu, C.-ting
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324821/
https://ncbi.nlm.nih.gov/pubmed/30586358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007872
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