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De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture
Inside the cell nucleus, genomes fold into organized structures that are characteristic of cell type. Here, we show that this chromatin architecture can be predicted de novo using epigenetic data derived from chromatin immunoprecipitation-sequencing (ChIP-Seq). We exploit the idea that chromosomes e...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5699090/ https://ncbi.nlm.nih.gov/pubmed/29087948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714980114 |
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