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De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture

Inside the cell nucleus, genomes fold into organized structures that are characteristic of cell type. Here, we show that this chromatin architecture can be predicted de novo using epigenetic data derived from chromatin immunoprecipitation-sequencing (ChIP-Seq). We exploit the idea that chromosomes e...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Di Pierro, Michele, Cheng, Ryan R., Lieberman Aiden, Erez, Wolynes, Peter G., Onuchic, José N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699090/
https://ncbi.nlm.nih.gov/pubmed/29087948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714980114
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