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De novo prediction of human chromosome structures: Epigenetic marking patterns encode genome architecture
Inside the cell nucleus, genomes fold into organized structures that are characteristic of cell type. Here, we show that this chromatin architecture can be predicted de novo using epigenetic data derived from chromatin immunoprecipitation-sequencing (ChIP-Seq). We exploit the idea that chromosomes e...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5699090/ https://ncbi.nlm.nih.gov/pubmed/29087948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714980114 |
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