Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomes

Pediatric diffuse midline glioma is a highly morbid glial neoplasm that may arise in the thalamus or brainstem (also known as diffuse intrinsic pontine glioma or DIPG). Because tumor anatomic location precludes surgical resection, diagnosis and treatment is based on MR imaging and analysis of biopsy...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Huang, Tina, Garcia, Roxanna, Qi, Jin, Lulla, Rishi, Horbinski, Craig, Behdad, Amir, Wadhwani, Nitin, Shilatifard, Ali, James, Charles, Saratsis, Amanda
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2018
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324678/
https://ncbi.nlm.nih.gov/pubmed/30647848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26430
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