In vitro effects of interleukin (IL)-1 beta inhibition on the epithelial-to-mesenchymal transition (EMT) of renal tubular and hepatic stellate cells

BACKGROUND: The epithelial to mesenchymal transition (EMT) is a multi-factorial biological mechanism involved in renal and hepatic fibrosis and the IL-1 beta has been assumed as a mediator of this process although data are not exhaustive. Therefore, the aim of our study was to evaluate the role of t...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Masola, Valentina, Carraro, Amedeo, Granata, Simona, Signorini, Lorenzo, Bellin, Gloria, Violi, Paola, Lupo, Antonio, Tedeschi, Umberto, Onisto, Maurizio, Gambaro, Giovanni, Zaza, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323803/
https://ncbi.nlm.nih.gov/pubmed/30616602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1770-1
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