The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones

OBJECTIVES: GPR142, which is highly expressed in pancreatic islets, has recently been deorphanized as a receptor for aromatic amino acids; however, its physiological role and pharmacological potential is unclear. METHODS AND RESULTS: We find that GPR142 is expressed not only in β- but also in α-cell...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Metab
Hlavní autoři: Rudenko, Olga, Shang, Jin, Munk, Alexander, Ekberg, Jeppe P., Petersen, Natalia, Engelstoft, Maja S., Egerod, Kristoffer L., Hjorth, Siv A., Wu, Margaret, Feng, Yue, Zhou, Yun-Ping, Mokrosinski, Jacek, Thams, Peter, Reimann, Frank, Gribble, Fiona, Rehfeld, Jens F., Holst, Jens J., Treebak, Jonas T., Howard, Andrew D., Schwartz, Thue W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323244/
https://ncbi.nlm.nih.gov/pubmed/30472415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.10.012
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky